
出生年月 :1981.05
民族:汉
学科专业:药物化学
研究方向:天然药物化学/真菌化学
电话:15827269869
电子邮箱:tfeng@mail.scuec.edu.cn
教育和工作简历:
1. 2020/1-至今,中南民族大学,TapTap点点,教授,博士生导师
2. 2019/7-2020/6,德国莱布尼兹汉诺威大学,访问学者
3. 2015/7-2019/12,中南民族大学,TapTap点点,副教授,硕士生导师
4. 2013/1-2015/6,中国科公司昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,副研究员
5. 2010/7-2012/12,中国科公司昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,助理研究员
6. 2005/9–2010/6,中国科公司昆明植物研究所,硕博连读,药物化学,博士
7. 2000/9–2004/7,西南大学,学士
科学研究:
主要从事天然产物化员工物学研究,聚焦真菌或药用植物特有天然产物的结构及其功能。获得新的天然产物700余个,多个分子被评为研究热点。主持国家自然科学基金3项,以及省部级等科研项目13项,在Org Lett、Chinese Chem Lett、Org Chem Front、J Agri Food Chem等多种学术期刊以第一作者或通讯作者发表研究论文170余篇,其中在自然指数期刊发表研究论文11篇;获授权专利5项。
主要荣誉、获奖和社会兼职:
国家民委中青年英才;中国科公司卢嘉锡青年人才奖;中国科公司经理优秀奖;中国科公司青年创新促进会会员;云南省自然科学奖励一、二等奖;中国菌物学会菌物化学专业委员会副主任;湖北省药学会药化专委会委员;中南民族大学第七届三育人标兵;国际期刊Natural Products and Bioprospecting、Journal of Fungi、Food & Medicine Homology期刊编委。
主要论著:
1. Juan He,# Jiao-Xian Du,# Qian-Ru Zhao,# Ya-Pei Liu, Yan-Long Yang,* Ji-Kai Liu,* Tao Feng*. Biochemical and genetic basis of guanacastane diterpene biosynthesis in basidiomycete fungi. Organic Letters 2023, 25, 5345-5349.
2. Jing Li, Wen-Xuan Wang, Zheng-Hui Li, Juan He, Rong Huang, Yong-Sheng Zheng, Lan-Qing Li, Xian Wang, Tao Feng*, Ji-Kai Liu*. Xylaridines C and D, unusual thiopyranodipyridine alkaloids from the fungus Xylaria longipes. Organic Letters 2019, 21, 6145−6148.
3. Jing Li, Wen-Xuan Wang, He-Ping Chen, Zheng-Hui Li, Juan He, Yong-Sheng Zheng, Huan Sun, Rong Huang, Qing-Xia Yuan, Xian Wang, Tao Feng*, Ji-Kai Liu*. (±)-Xylaridines A and B, highly conjugated alkaloids from the fungus Xylaria longipes. Organic Letters 2019, 21, 1511-1514.
4. Wen-Xuan Wang, Xin-Xiang Lei, Hong-Lian Ai, Xue Bai, Jing Li, Juan He, Zheng-Hui Li, Yong-Sheng Zheng, Tao Feng*, Ji-Kai Liu*. Cytochalasans from the endophytic fungus Xylaria cf. curta with resistance reversal activity against fluconazole-resistant Candida albicans. Organic Letters 2019, 21, 1108−1111.
5. Wen-Xuan Wang, Xin-Xiang Lei, Yan-Ling Yang, Zheng-Hui Li, Hong-Lian Ai, Jing Li*, Tao Feng*, Ji-Kai Liu*. Xylarichalasin A, a halogenated hexacyclic cytochalasan from the fungus Xylaria cf. curta. Organic Letters 2019, 21, 6957-6960.
6. Tao Feng, Kai-Ting Duan, Shi-Jun He, Bin Wu, Yong-Sheng Zheng, Hong-Lian Ai, Zheng-Hui Li, Juan He, Jian-Ping Zuo*, Ji-Kai Liu*. Ophiorrhines A and B, two immunosuppressive monoterpenoid indole alkaloids from Ophiorrhiza japonica. Organic Letters 2018, 20, 7926–7928
7. Wei Li, Juan He, Tao Feng*, Hui-Xiang Yang, Hong-Lian Ai, Zheng-Hui Li, Ji-Kai Liu*. Antroalbocin A, an antibacterial sesquiterpenoid from higher fungus Antrodiella albocinnamomea, Organic Letters 2018, 20, 8019–8021
8. Hui-Xiang Yang, Hong-Lian Ai, Tao Feng*, Wen-Xuan Wang, Bin Wu, Yong-Sheng Zheng, Huan Sun, Juan He, Zheng-Hui Li, Ji-Kai Liu*. Trichothecrotocins A–C, antiphytopathogenic agents from potato endophytic fungus Trichothecium crotocinigenum. Organic Letters 2018, 20, 8069–8072
9. Tao Feng, Xue-Mei Li, Jun He, Hong-Lian Ai, He-Ping Chen, Xiao-Nian Li, Zheng-Hui Li*, Ji-Kai Liu*. Nicotabin A, a sesquiterpenoid derivative from Nicotiana tabacum. Organic Letters 2017, 19, 5201−5203.
10. Tao Feng, Yan Li, Ya-Ping Liu, Xiang-Hai Cai, Yuan-Yuan Wang, and Xiao-Dong Luo*. Melotenine A, a cytotoxic monoterpenoid indole alkaloid from Melodinus tenuicaudatus, Organic Letters 2010, 12(5), 968-971.
11. Tao Feng, Xiang-Hai Cai, Yan Li, Yuan-Yuan Wang, Ya-Ping Liu, Ming-Jin Xie, Xiao-Dong Luo*. Melohenines A and B, two unprecedented alkaloids from Melodinus henryi, Organic Letters 2009, 11(21), 4834-4837.
12. Juan He1, Jiao-Xian Du1, Meng Wang, Xiao-Dong Luo*, Tao Feng*. Irpexlactones A and B, a pair of ring-rearranged tremulane sesquiterpenoids from the basidiomycete Irpex lacteus and their anti-inflammatory activity. Chinese Chemical Letters 2025 (in press, https://doi.org/10.1016/j.cclet.2024.110769).
13. Shan-Shan Huang, Hui-Xiang Yang, Juan He, Ji-Kai Liu, Tao Feng*. Discovery of a biocontrol strain Trichaptum laricinum: its metabolites and antifungal activity against pathogenic fungus Colletotrichum anthrisci. Journal of Agricultural and Food Chemistry 2024, 72, 13154-13163.
14. Jin-Tao Ma,# Xin-Yue Dong,# Zheng-Hui Li, He Yan, Juan He,* Ji-Kai Liu,* Tao Feng*. Antibacterial metabolites from kiwi endophytic fungus Fusarium tricinctum, a potential biocontrol strain for kiwi canker disease. Journal of Agricultural and Food Chemistry 2023, 71, 7679-7688.
15. Hong-Lian Ai, Bao-Bao Shi, Wei Li, Juan He, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*. Bipolarithizole A, an antifungal phenylthiazole-sativene merosesquiterpenoid from the potato endophytic fungus Bipolaris eleusines. Organic Chemistry Frontiers 2022, 9, 1814-1918.
16. Ying Huang, Shuai-Bing Zhang, He-Ping Chen, Zhen-Zhu Zhao, Zhong-Yu Zhou, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*. New acetylenic acids and derivatives from the edible mushroom Craterellus lutescens (Cantharellaceae). Journal of Agricultural and Food Chemistry 2017, 65, 3835−3841.
17. He-Ping Chen, Zhen-Zhu Zhao, Zheng-Hui Li, Ying Huang, Shuai-Bing Zhang, Yang Tang, Jian-Neng Yao, Lin Chen, Masahiko Isaka, Tao Feng*, Ji-Kai Liu*, Anti-proliferative and anti-inflammatory lanostane triterpenoids from the Polish edible mushroom Macrolepiota procera. Journal of Agricultural and Food Chemistry 2018, 66, 3146-3154.
18. Tao Feng, Jin-Long Cai, Xue-Mei Li, Zhong-Yu Zhou, Zheng-Hui Li, and Ji-Kai Liu, Chemical constituents and their bioactivities of mushroom Phellinus rhabarbarinus. Journal of Agricultural and Food Chemistry 2016, 64, 1945−1949.
19. Tao Feng, Jia Su, Zhi-Hui Ding, Yong-Tang Zheng, Yan Li, Ying Leng, and Ji-Kai Liu, Chemical constituents and their bioactivities of “Tongling White Ginger” (Zingiber officinale), Journal of Agricultural and Food Chemistry 2011, 59, 11690-11695.
20. Shuai-bing Zhang, Ying Huang, Shi-jun He, He-ping Chen, Bin Wu, Shan-yong Li, Zhen-zhu Zhao, Zheng-hui Li, Xian Wang, Jian-ping Zuo, Tao Feng*, Ji-Kai Liu*. Heterocyclic compounds from the mushroom Albatrellus confluens and their inhibitions against lipopolysaccharides-induced B lymphocyte cell proliferation. Journal of Organic Chemistry 2018, 83, 10158−10165.
21. Zhen-Zhu Zhao, He-Ping Chen, Bin Wu, Ling Zhang, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*. Matsutakone and matsutoic acid, two (nor)steroids with unusual skeletons from the edible mushroom Tricholoma matsutake. Journal of Organic Chemistry 2017, 82, 7974−7979.
22. Xiao-Fang Zhang1, Hong-Fei Li1, Hui Liu, Fang-Lu Wei, Jiao-Xian Du, Ji-Kai Liu*, Juan He*, Tao Feng*. Sesquiterpenoids from Carpesium abrotanoides and their anti-inflammatory activity both in vitro and in vivo. Bioorganic Chemistry 2024, 151, 107684.
23. Ming-Xuan Gao, Feng Wu, Si-Qiong Teng, He-Ping Chen, Zheng-Hui Li, Juan He,* Tao Feng,* Ji-Kai Liu*. Triquinane sesquiterpene glycosides from the basidiomycete Antrodiella zonata. Journal of Natural Products 2023, 86, 1736-1745.
24. Bao-bao Shi, Hong-Lian Ai, Kai-Ting Duan, Tao Feng*, Ji-Kai Liu*. Ophiorrhines F and G, key biogenetic intermediates of ophiorrhine alkaloids from Ophiorrhiza japonica and their immunosuppressant activities. Journal of Natural Products 2022, 85, 453-457.
25. Juan He, Rui Ma, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*. Taccachatrones A−G, highly oxidized steroids from the rhizomes of Tacca chantrierii and their cytotoxicity assessment. Journal of Natural Products 2021, 84, 2265−2271.
26. Meng Wang, Jiao-Xian Du, Yang Hui-Xiang, Quan Dai, Ya-Pei Liu, Juan He, Yi Wang, Zheng-Hui Li, Tao Feng,* Ji-Kai Liu*. Sesquiterpenoids from cultures of the basidiomycetes Irpex lacteus. Journal of Natural Products 2020, 83, 1524-1531.
27. Ya-Pei Liu, Quan Dai, Wen-Xuan Wang, Juan He, Zheng-Hui Li, Tao Feng,* Ji-Kai Liu, Psathyrins: antibacterial diterpenoids from Psathyrella candolleana. Journal of Natural Products 2020, 83, 1725-1729.
28. Tao Feng, Xiao-Qing Gan, Yun-Li Zhao, Shuai-Bing Zhang, He-Ping Chen, Juan He, Yong-Sheng Zheng, Huan Sun, Rong Huang, Zheng-Hui Li*, Ji-Kai Liu*. Tricholopardins A and B, anti-inflammatory terpenoids from the fruiting bodies of Tricholoma pardinum. Journal of Natural Products 2019, 82, 45−50.
29. Fa-Lei Zhang, Tao Feng*. Diterpenes specially produced by fungi: Structures, biological activities and biosynthesis (2010–2020). Journal of Fungi 2022, 8, 244.
30. Quan Dai, Fa-Lei Zhang, Zheng-Hui Li, Juan He*, Tao Feng*. Immunosuppressive sesquiterpenoids from the edible mushroom Craterellus odoratus. Journal of Fungi 2021, 7, 1052.
31. 何隽、冯涛。《土家族常用要用植物化学》,2024,ISBN 978-7-5706-3285-5,湖北科学技术出版社。
32. 冯涛、刘吉开、李小军、董新月、何隽。一种棕灰口蘑提取物在制备防治炎症性肠病药物中的应用,2024,中国,ZL202211669811.1。
33. 冯涛、刘吉开、杨会祥。一种二萜类衍生物及其制备方法与镇痛药物、小脆柄菇发酵得物及其乙酸乙酯萃取液,2023,中国,ZL202210290942.2
34. 冯涛、艾洪莲、何隽、杨会祥、李正辉、刘吉开。马铃薯内生菌具有抗病原菌活性的发酵有机物、其制备工艺、应用以及发酵产物,2021,ZL202010714851.8
35. 冯涛、刘吉开、何隽、李正辉、石晨。口蘑三萜化合物、其制备方法、提取物及其应用,2021,中国,ZL202010980531.7
36. 冯涛、刘吉开、李正辉。口蘑菌素甲及其制备方法与应用、口蘑菌素乙及其制备方法与应用,2019,中国, ZL201810010131.6